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Safety and Performance Requirements for Cabinet X-ray Security Screening and Industrial Quality Control Systems

This guidance is intended to assist manufacturers of cabinet X-ray systems with meeting the requirements of the Federal Food, Drug, and Cosmetic Act and applicable federal radiation safety regulations. It applies to cabinet X-ray systems used primarily for security screening and industrial quality control, including systems for inspecting baggage, food, circuit boards, and tires.

  1. Implement comprehensive quality control and testing program
  2. Develop complete technical documentation including:
    • Design specifications
    • Test procedures and results
    • Quality control procedures
    • Maintenance schedule
  3. Prepare and submit required product report before market entry
  4. Establish system for maintaining required records
  5. Implement process for accident reporting and recalls if needed
  6. Ensure proper labeling including certification, warnings and identification
  7. Establish annual reporting process
  8. For imported systems, designate US agent
  9. Train personnel on regulatory requirements and compliance procedures
  10. Regularly review compliance status and update documentation as needed

Key Considerations

Non-clinical testing

  • Testing must demonstrate compliance with emission limit of 0.5 milliRoentgen in one hour at any point 5cm outside external surface
  • Measurements must be averaged over 10 square cm area with no linear dimension greater than 5cm
  • Testing must be done at maximum output settings

Human Factors

  • Insertion of any part of human body through ports into primary beam must not be possible
  • For systems designed to admit humans:
    • Internal control to prevent/terminate X-ray generation
    • No means to initiate X-rays from inside
    • Audible and visible warning signals for 10 seconds before X-ray generation
    • Visible warning signal during X-ray generation

Labelling

  • Certification label permanently affixed stating compliance with standards
  • Warning labels at controls: “Caution: X-Rays Produced When Energized”
  • Warning labels at ports: “Caution: Do Not Insert Any Part of the Body When System is Energized–X-ray Hazard”
  • Identification label with manufacturer name, place and date of manufacture

Safety

  • Minimum of two safety interlocks on each door
  • At least one safety interlock on each access panel
  • Ground fault must not result in X-ray generation
  • Key-actuated control required
  • Two independent X-ray ON indicators
  • Additional X-ray ON indicators visible from each door, access panel and port

Other considerations

  • NCRP 57: Instrumentation and Monitoring Methods for Radiation Protection
  • NCRP 112: Calibration of Survey Instruments Used in Radiation Protection

Original guidance

  • Safety and Performance Requirements for Cabinet X-ray Security Screening and Industrial Quality Control Systems
  • HTML / PDF
  • Issue date: 2007-09-18
  • Last changed date: 2020-03-24
  • Status: FINAL
  • Official FDA topics: Medical Devices, Radiation-Emitting Products
  • ReguVirta summary file ID: e46a4b67c497715b87f31e0edbc13498
This post is licensed under CC BY 4.0 by the author.